Study Finds Popular Cholesterol Drugs Vytorin, Zetia Not Effective

A recent study appearing in the New England Journal of Medicine has questioned the effectiveness of the popular cholesterol medication, Vytorin and its sister drug Zetia. Vytorin, a combination of Zetia and the generic drug Zocor, is the second most profitable pharmaceutical manufactured by Merck & Co. The Securities and Exchange Commission reports that sales of Vytorin and Zetia have raked in an astonishing $21 billion worldwide since 2003.

Although ezetimibe, the active ingredient in Vytorin and Zetia, has been shown to reduce cholesterol slightly, its ability to unclog coronary arteries is less than that of niacin, a cheap B vitamin, often available over the counter, according to the article. Additionally, Vytorin and Zetia competitors have been shown to prevent heart attacks, strokes and other cardiovascular diseases at a less expensive price tag, whereas Zetia and Vytorin have not been proven to do either, according to the study. In contrast to Lipitor, Zocor and other statin-type drugs which block cholesterol production in the Liver, Zetia prevents cholesterol absorption in the intestines. The difference between how the drugs reduce cholesterol has helped Zetia’s popularity, despite the fact its effectiveness has been questioned. Many patients have been prescribed Vytorin as an alternative to the unconfortable side effects of Niacin and other statins’ including liver problems.

This is the third study in the last two years that has cast doubt on the effectiveness of the pharmaceutical giant. Additionally, in August 2009, Merck and Schering-Plough agreed to pay $41.5 million to settle class-action lawsuits accusing the companies of withholding unfavorable information about the drugs. Due to their recent merge in Nov. 2009, both companies are responsible for the lawsuit. Vytorin has been linked to potentially harmful side effects, including a high rate of cancer deaths, according to a controversial study released in 2008.

These studies also question whether the Food and Drug Administration prematurely approved the drugs without requiring additional studies that illustrate the drugs’ effectiveness or ability to prevent heart attacks. Merck waited three years before starting a research study to examine the effect on heart attack rates among Zetia and Vytorin patients.

Additional studies will be conducted to further examine the effectiveness of the drugs, including heart attack prevention; however results are not expected to be available until at least 2012. Leading cardiologists have advised patients to use cholesterol drugs like Zetia and Vytorin only if his or her cholesterol levels have not improved with the use of other medications and life-style changes. Oftentimes, patients pursue a Vytorin lawsuit to seek monetary compensation to cover medical treatments due to cardiovascular complications.

Disability is no more a hurdle to your child life

Disability of the child is major concern for parents when they have one. God blesses these people with some additional talent for giving them disability. Parents who are concerned about their disability tend to ignore their born talent of these children. Only education can polish their unbelievable talent and showcase it to the rest of the world. Education is the only thing that can make the necessary difference in their life. If your child is visually impaired, it becomes impossible to pursue normal education under integrated education system. Understanding the need and importance of education in the life of visually impaired children, non-profit organisations like Soch have come forward to provide free schoolfor blind with an integrated education system. The curriculum of education for blind includes value based education along with self-help & life skills, entertainment, sports & games are the part of their routine. The self -help life skills learnt at Soch School for blind helped them to establish an independent life in the society. The integrated education system fallowed at school for blind help the non-profit organisation to include the disabled children into mainstream. The integrated education system at Soch was able to send 10 batches to SSC board examination till date. Many of the blind children who have pursued their basic education at Soch have been placed in the government organisation in respected cadres. Education system at Soch aims at providing quality education to blind so, they provide all the necessary resources to disabled children when some special attention is required. Many of the children who are suffering from visual disability are kept away from schooling due to their inability to adapt into normal education system. If your child is one among them, join them with the school for blind that is run by non-profit organisation Soch. The service offered by the non-profit organisation is named as SUNETHRA. The organisation is running both residential and day care education in the school for blind. Not only that, the non-profit organisation tries to meet all the basic needs like lodging, boarding, education, medical & clothing. The integrated education system at Soch also includes vocational courses apart from their regular education. This curriculum is tailored to develop some special skills for empowering children in rural and semi- urban areas. There is no need to keep your child away from schooling due to his/her visual disability. You can provide a value based education to children by joining them at school for blind Soch.

The Healthy New Mother Will Be More Happy

People often say, woman who have been the mother are real woman. Yeah, no matter for the husband or wife speaking, to have a baby is a great event of life full of toil and pain, it contains hope and happiness. If you have been a mother, sincerely hope that our some Suggestions will bring you some help; make your life more healthy and happy.

1, slowly moving about. Now the rhythm of the life is more and more quickly, but kids action is always the most natural, most leisurely, unlike the adults that always hurried. Now you are, should be consistent with the child, slowly and don’t make your weak body overwork or catch cold.

2, take the time to get more sleep. When the children get asleep, or someone takes care, you might as well have a nap. Maybe someone feel sleeping in the daytime is lazy, is a waste of time. But don’t forget: taking care of the children is very hard, and will cost much energy. Sleeping is the best rest, only physical custody of good, rested; it will be possible to do other thing well.

3, little worry about, much enjoyment. as the new mother you, now most should do is devotedly taking good care of the children and her own body. You may let others do more; you don’t need to feel sorry. Only you restore well again, can you take good care of children and the home. Had a hot bath, flip the past like and have time to watch novel, or have a chat with family and friends, walk, can make your spirit glows. I’m afraid such chance only once, experience it well.

4, positively and optimistically live. You should Communicate with the outside world, maintain good relations with family and friends. Whether in pregnancy or postpartum recovery phase, and external communication is very important. This can not only from experience people get many practical knowledge and skill, but to a great extent, to make you relieve pressure, get rid of loneliness. It is better to especially with those women in pregnancy and birth. You can often come out around call, a walk with your kids, when mother exchange of pleasure and pain, will make your life colorful.

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Mother Shipton and the End of London

Born in 1488 as Ursula Southeil, Mother Shipton came to be known as one of the most famous soothsayers in history. She was born in a cave in Knaresborough, Yorkshire and was said to been absolutely hideous to look at, but apparently had a knack for prophesy. She told fortunes for the locals, while on the side writing her predictions about the world at large.

While the majority of her predictions dealt with local and regional issues, her flair for the dramatic was best illustrated in her predictions about London. Her work came out in two publications, both nearly 60 years after her death in 1561.

She like other clairvoyants line Edgar Cayce and Maria Taigi, predicted great world changes in the years to come. She made general prediction centered on her region of the country but also had words for the greater world around her. Hers was one of the first well-documented cases of prediction, which included a vision for things inconceivable in her time. She predicted electronic communication, motorized vehicles, and tunnels that went through entire mountains, transportation under water. She also predicted that men would fly, cruise around the world in Iron Ships and that great discoveries of gold would be made in countries not yet discovered.

Her most famous prediction it is told, mentioned the Great Fire of London, which occurred inside the walls of the medieval roman cities and nearly burned the entire city to the ground. Samuel Pepys, a Member of Parliament and Naval administrator noted that when the great fire occurred, Mother Shipton had been the one to accurately foretell it. Her last prediction concerning the end of the world was that London would no longer exist prior to it.

So, those of you who wish to see the great city before it disappears can stay in any number of Mayfair hotels to make a comfortable, luxury home base from which to see the amazing city before its too late. London hotels can provide all manner of tourist information to help you organize your trip throughout London and direct you to sites of interest fitting of your budget.

The Most Important Tool in a Students Study Arsenal College Textbooks

Studying in college is clearly one of the most vital tools a student has, to achieve their goal of a degree. Textbooks are the most important tool in a student’s study arsenal. Without securing the necessary books, a student risks falling behind and failing to do his best.

Securing books prior to the start of the semester is the best move a student can make. Professors often assign work right from the very first class, and delaying the purchase of books can be a devastating error. Thankfully, several avenues exist for procuring the necessary textbooks. Purchasing textbooks is a solution that works for many students. Being able to use the books for reference even after the conclusion of a class is appealing to many students. If a student opts not to retain the book, buyback programs will help the student recoup some of their costs at the end of the semester.

Other students choose to rent their textbooks. Renting allows a student to have the necessary book for the semester, but doesn’t require the cash outlay that buying a book would. It is also environmentally friendly, as books are returned to the textbook company, rather than possibly ending up in a landfill.

Once the necessary materials are secured, the student is ready to meet their educational goals. A students methods of study will greatly influence the outcome. Students should ask themselves the following questions when setting up their study plan of action: -How do I learn best? -How will I be asked to recall the information? -When do I do my best studying?

Some students find outlines to be the best study tool. Others prefer flashcards. Some find discussing the subject during a study session with other students to be most beneficial.

Studying for an essay test is very different than studying for a multiple choice exam. Knowing what type of exam is being given will aid the student in choosing their study methods. If the exam is essay form, outlining answers to some possible questions will provide a handy framework. Outlining class notes and careful review of the text is often vital to preparing for any exam.

All night cram sessions can work, but most students do best with a more moderate study schedule. Larks and night owls each need to find a study schedule that works with their biological clock. Steady sleep schedules will go a long way toward college success.

Academic success is an important goal, and the right materials, study skills, and rest, will aid any student in their quest.